Human umbilical cord cells for cardiovascular tissue engineering: a comparative study
نویسندگان
چکیده
منابع مشابه
Human umbilical cord cells for cardiovascular tissue engineering: a comparative study.
OBJECTIVE Tissue engineering of viable, autologous cardiovascular replacements with the potential to grow, repair and remodel represents an attractive approach to overcome the shortcomings of available replacements for the repair of congenital cardiac defects. Currently, vascular myofibroblast cells represent an established cell source for cardiovascular tissue engineering. Cell isolation requi...
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Widespread use of human umbilical cord cells for cardiovascular tissue engineering requires production of large numbers of well-characterized cells under controlled conditions. In current research projects, the expansion of cells to be used to create a tissue construct is usually performed in static cell culture systems which are, however, often not satisfactory due to limitations in nutrient a...
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Heart failure is one of the leading causes of death worldwide. End stage disease often requires heart transplantation, which is hampered by donor organ shortage. Tissue engineering represents a promising alternative approach for cardiac repair. For the generation of artificial heart muscle tissue several cell types, scaffold materials and bioreactor designs are under investigation. In this revi...
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Cell sources and tissue integration between cartilage and bone regions are critical to successful osteochondral regeneration. In this study, human umbilical cord mesenchymal stromal cells (hUCMSCs), derived from Wharton's jelly, were introduced to the field of osteochondral tissue engineering and a new strategy for osteochondral integration was developed by sandwiching a layer of cells between ...
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INTRODUCTION: Tissue engineering and ex vivo gene therapy can be used synergically as a tool to regenerate bone that overcomes the problems of currently available bone replacements. Recently, in our lab a new source of mesenchymal stem cells (MSCs) has been found in the umbilical cord; Human Umbilical Cord Perivascular cells (HUCPVCs) provide an alternative to bone marrow derived MSCs. Due to t...
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ژورنال
عنوان ژورنال: European Journal of Cardio-Thoracic Surgery
سال: 2004
ISSN: 1010-7940
DOI: 10.1016/j.ejcts.2003.12.038